Integrity

Anika Therapeutics Ltd

Lewins Mead/Bristol, United Kingdom

Anika. Restore Active Living.® Anika is a global joint preservation company that creates and delivers meaningful advancements in early intervention orthopedic care. We partner with clinicians to understand what they need most to treat their patients and we develop minimally invasive products that restore active living for people around the world. We are committed to leading in high opportunity spaces within orthopedics, including osteoarthritis pain management, and regenerative solutions. Our Focus Since our incorporation in 1992, Anika has evolved into a market leader in joint preservation. Our comprehensive portfolio of solutions for osteoarthritis pain management, and regenerative solutions, provides expansive treatment options for managing and addressing joint pain across the early intervention continuum of care. Our broad portfolio provides patient care options by managing pain, thus delaying or avoiding a more invasive procedure, and in some cases, slowing the progression of osteoarthritis. With solutions ranging from viscosupplement injections to treat osteoarthritis pain, and regenerative solutions that repair damaged tissues and tendons, our focus is to restore active living and help people stay active. Anika’s culture is defined by its employees who are purpose-driven and passionate about our vision to be a global leader in joint preservation solutions that restore active living for people around the world. Our Products and Technology Osteoarthritis (OA) Pain Management With over 30 years of global expertise developing, manufacturing and commercializing products based on hyaluronic acid (HA), a naturally occurring polymer found throughout the body and vital for proper joint health and tissue function, we are a leader in viscosupplement injectables for osteoarthritis (OA) pain management. Our key OA pain viscosupplement products include Orthovisc and Monovisc , which are exclusively marketed and sold in the US through the DePuy Synthes division of Johnson and Johnson and outside the US by Anika and our wide network of global commercial partners, and Cingal , an HA-based combination viscosupplement with steroid injectable, currently available in more than 35 countries outside the US through a wide network of global commercial partners. Regenerative Solutions Our portfolio of orthopedic regenerative solutions is driven by our proprietary HA technologies. These products include Hyalofast , an off-the-shelf, single stage, 100% hyaluronic acid-based scaffold for cartilage repair that supports hyaline-like cartilage regeneration, available in more than 35 countries outside the US, Integrity , an HA-based scaffold for rotator cuff repair and other tendon repair procedures that provides reliable strength and supports tissue regeneration, and Tactoset , an HA-enhanced injectable, settable bone substitute that supports cell-mediated regeneration of new bone and is designed to treat insufficiency fractures and augment hardware, such as suture anchors.